FDA updates vinca alkaloid labeling for preparation in intravenous infusion bags only
[4/21/22] FDA worked with drug application holders to remove instructions for preparation of vinca alkaloids by syringe and to recommend preparation in intravenous infusion bags only. These labeling updates are complete, and the updated prescribing information for vinca alkaloids now contains instructions for health care professionals to only prepare these drugs in intravenous infusion bags. [1/15/21] The U.S. Food and Drug Administration is alerting health care professionals to labeling updates for the preparation of vinca alkaloids, a group of chemotherapy agents that includes vincristine sulfate injection, vinblastine sulfate (for) injection, and vinorelbine tartrate injection. To reduce the potential for unintended intrathecal (spinal) administration, which causes death or severe neurological injury, FDA is workin...